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- MBS Monoclonals
- RAT ANTI MOUSE CD11a Antibody
Product short description
Price:
205 EUR
Size:
0.025 miligrams
Catalog no.:
GEN214970
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Also known as
CD11a
Gene name
CD11a
Immunoglobulin isotype
IgG2a
Clone
I21/7
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Host organism
Rat (Rattus norvegicus)
Concentration
IgG concentration 1.0 mg/ml
Latin name
Mus musculus,Rattus norvegicus
Form/Appearance
Purified (Purified IgG - liquid)
Tested applications:
Immunoprecipitation (IP), Flow Cytometry (FACS)
Other gene names
Itgal; Itgal; Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A; Lfa-1; Ly-15; LFA-1A; Ly-15
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Other names
Integrin alpha-L; Integrin alpha-L; integrin alpha-L; alpha L integrin; lymphocyte antigen 15; CD11 antigen-like family member A; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; lymphocyte function associated antigen 1, alpha polypeptide; integrin alpha L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15
Specificity and cross-reactivity
CD11a This item recognises murine CD11a, a 170 - 180kD type I membrane glycoprotein, which is also known as the integrin alphaL subunit. CD11a is a member of the intergrin family of adhesion molecules. The CD11a molecule is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM-1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes. Clone I21/7 is reported to block the cytolytic activity of cytotoxic T cell lines; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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