RAT ANTI MOUSE DECTIN-2:Biotin Antibody

221 EUR

0.025 miligrams

GEN216083

N/A

IgG2a

D2.11E4

DECTIN-2

anticorps

Monoclonal

Antibodies

Biotinylated

Mnoclonal antibodies

Flow Cytometry (FACS)

Rat (Rattus norvegicus)

Mus musculus,Rattus norvegicus

IgG concentration 0.1 miligram per 1 mililiter

Biotin (Purified IgG conjugated to Biotin - liquid)

Clec4n; Clec6a; Nkcl; Clec6a; Clecsf10; Clec4n; Clecsf10; Dectin2; DC-associated C-type lectin 2; Dectin-2

Clec4n; Clec6a; Nkcl; Clec6a; Clecsf10; Clec4n; Clecsf10; Dectin2; DC-associated C-type lectin 2; Dectin-2

Clec4n; Clec6a; Nkcl; Clec6a; Clecsf10; Clec4n; Clecsf10; Dectin2; DC-associated C-type lectin 2; Dectin-2

Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

C-type lectin domain family 6 member A isoform 3; C-type lectin domain family 6 member A; C-type lectin domain family 6 member A; dectin-2; DC-associated C-type lectin 2; natural killer complex lectin; C-type lectin superfamily member 10; dendritic cell-associated C-type lectin 2; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10; C-type lectin domain family 4, member n; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2

DECTIN-2 Recognises mouse DC-associated C-type lectin-2 (Dectin-2), a type II transmembrane protein that is a member of the C-type lectin superfamily. In mouse, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells. Clone D2.11E4 does not stain brain microglia or meningeal macrophages. _x000D__x000D_Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation. _x000D__x000D__x000D_The function of dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.