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- RAT ANTI MOUSE Ly-6A/E:APC Antibody
Product short description
Price:
603 EUR
Size:
100 Tests
Catalog no.:
GEN217390
Product detailed description
Clone
D7
Gene name synonims
N/A
Purification method
N/A
Immunoglobulin isotype
IgG2a
Also known as
Ly-6A/E
Gene name
Ly-6A/E
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Subcategory
Mnoclonal antibodies
Tested applications:
Flow Cytometry (FACS)
Host organism
Rat (Rattus norvegicus)
Latin name
Mus musculus,Rattus norvegicus
Concentration
IgG concentration 0.1 miligram per 1 mililiter
Form/Appearance
APC (Purified IgG conjugated to Allophycocyanin (APC) - liquid)
Other gene names
Ly6a; Ly6a; TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1; Ly6; Ly-6A.2/Ly-6E.1; SCA-1; TAP
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.
Other names
lymphocyte antigen 6A-2/6E-1; Lymphocyte antigen 6A-2/6E-1; lymphocyte antigen 6A-2/6E-1; stem cell antigen 1; T-cell-activating protein; lymphocyte antigen 6 complex, locus A; Stem cell antigen 1; SCA-1; T-cell-activating protein
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Storage and shipping
Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. DO NOT FREEZE. the antibody should be stored undiluted. the antibody is photosensitive and should be protected from light. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. Shelf Life: 12 months from date of dispatch.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
Ly-6A/E This item recognises members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically, it recognises Ly-6A.2 and Ly-6E.1. Ly-6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly-6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells. _x000D__x000D_Clone D7 (MBS214527) has been reported to induce T cell activation.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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