MOUSE Anti-SOS1 Antibody

370 EUR

100ug

GEN217406

N/A

N/A

SOS1

SOS1

IgG1

SOS-1

anticorps

Monoclonal

Antibodies

Mus musculus

Mouse (Mus musculus)

Mnoclonal antibodies

IgG concentration 1.0mg/ml

Purified (Purified IgG - liquid)

SOS1; SOS1; GF1; HGF; NS4; GGF1; GINGF; SOS-1

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

son of sevenless homolog 1; Son of sevenless homolog 1; son of sevenless homolog 1; SOS-1; guanine nucleotide exchange factor; gingival fibromatosis, hereditary, 1; son of sevenless homolog 1 (Drosophila); N/A

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

SOS1 This item specifically recognises SOS1 (son of sevenless homolog 1), a ubiquitously expressed 150kDa intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases. _x000D__x000D_Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as gingival fibromatosis 1 (GINGF1), and also the cause of the relatively common autosomal dominant disorder Noonan syndrome type 4 (NS4), characterized by short stature, congenital heart malformation, bleeding diathesis and distinctive facial features.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.