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- MBS Monoclonals
- MOUSE Anti-HUMAN CD243 Antibody
Product short description
Price:
1056 EUR
Size:
1 mililiter
Catalog no.:
GEN219390
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Concentration
N/A
Immunoglobulin isotype
IgG1
Also known as
CD243
Gene name
CD243
Clone
JSB-1
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Latin name
Mus musculus
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Form/Appearance
Concentrate (Concentrated Tissue Culture Supernatant - liquid)
Tested applications:
Immunohistology - Paraffin (IHC), Immunohistology - Frozen (IHC)
Other gene names
ABCB1; ABCB1; CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; MDR1; PGY1
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
multidrug resistance protein 1; Multidrug resistance protein 1; multidrug resistance protein 1; P-glycoprotein 1; colchicin sensitivity; doxorubicin resistance; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Specificity and cross-reactivity
CD243 This item recognises the 170-180kD P-glycoprotein, CD243, a plasma membrane associated molecule which is important in mediating resistance to cytotoxic drugs. In normal tissues P-glycoprotein is expressed in liver, kidney, colon, adrenal gland and lung. In malignant conditions increased expression of P-glycoprotein may be associated with multi-drug resistance, and the detection of this can have important consequences for treatment. This clone has also been reported to be suitable for Western blot analysis.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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