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- MBS Monoclonals
- HAMSTER ANTI MOUSE BIM Antibody
Product short description
Price:
531 EUR
Size:
0.25 miligrams
Catalog no.:
GEN219506
Product detailed description
Also known as
BIM
Gene name
BIM
Gene name synonims
N/A
Immunoglobulin isotype
IgG
Purification method
N/A
Clone
151-149
Host organism
Hamster
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Latin name
Mus musculus
Subcategory
Mnoclonal antibodies
Concentration
IgG concentration 1.0mg/ml
Form/Appearance
Purified (Purified IgG - liquid)
Tested applications:
Flow Cytometry (FACS), Immunofluorescence (IF)
Other gene names
Bcl2l11; Bcl2l11; Bim; Bod; 1500006F24Rik; Bim; Bcl2-L-11
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.
Other names
bcl-2-like protein 11 isoform 3; Bcl-2-like protein 11; bcl-2-like protein 11; bcl2-L-11; Bcl2 interacting mediator of cell death; bcl2-interacting mediator of cell death; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Armenian of Syrian hamster monoclonal IgGs are useful antibodies for double staining your IHC samples. Using mabs or monoclonal antibodies has a lot of advantages for Flow cytometry.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Specificity and cross-reactivity
BIM This item is specific for human Bcl-2 interacting mediator of cell death (Bim), also known as Bod. Bim is a pro-apoptotic protein within the Bcl-2 family, which functions within the intrinsic apoptosis pathway. Bim is known to interact with pro-survival proteins including Bcl-2, Bcl-XL and Bcl-w._x000D__x000D_It is expressed in a variety of cell types, where it is maintained in an inactive conformation by phosphorylation or through binding to the microtubule-associated dynein motor complex. Upon certain apoptotic stimuli, Bim is released from microtubules and mediates caspase-dependent apoptosis._x000D_; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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