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- MBS Monoclonals
- HAMSTER ANTI MOUSE CD278 Antibody
Product short description
Price:
437 EUR
Size:
0.25 miligrams
Catalog no.:
GEN219570
Product detailed description
Gene name synonims
N/A
Immunoglobulin isotype
IgG
Purification method
N/A
Also known as
CD278
Gene name
CD278
Clone
C398.4A
Host organism
Hamster
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Latin name
Mus musculus
Subcategory
Mnoclonal antibodies
Concentration
IgG concentration 500ug/1000ul
Form/Appearance
Purified (Purified IgG - liquid)
Other gene names
ICOS; ICOS; AILIM; CD278; CVID1; AILIM
Tested applications:
Immunoprecipitation (IP), Immunohistology - Frozen (IHC), Flow Cytometry (FACS)
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.
Other names
inducible T-cell costimulator; Inducible T-cell costimulator; inducible T-cell costimulator; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule; inducible T-cell co-stimulator; Activation-inducible lymphocyte immunomediatory molecule
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Armenian of Syrian hamster monoclonal IgGs are useful antibodies for double staining your IHC samples. Using mabs or monoclonal antibodies has a lot of advantages for Flow cytometry.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Specificity and cross-reactivity
CD278 This item recognises CD278, also known as Inducible T cell costimulator or ICOS, a CD28-superfamily costimulatory molecule. It is expressed on activated T cells and resting memory T cells. It enhances all the basic T cell responses to a foreign antigen, namely proliferation, secretion of lymphokines and up-regulation of molecules that mediate cell-cell interaction. It is essential for the efficient interaction between B and T cells and is involved in antibody responses to T cell dependent antigens. It up-regulates the synthesis of interleukin-10, but not interleukin-2 and prevents the apoptosis of pre-activated T cells. Clone C398.4A has been reported to costimulate T cell activation and proliferation in vitro.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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