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- MBS Monoclonals
- MOUSE Anti-RABBIT MHC CLASS II DQ Antibody
Product short description
Price:
564 EUR
Size:
0.25 miligrams
Catalog no.:
GEN219844
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Clone
2C4
Other names
N/A
Purification method
N/A
Immunoglobulin isotype
IgG2a
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Also known as
MHC CLASS II DQ
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Concentration
IgG concentration 1.0mg/ml
Form/Appearance
Purified (Purified IgG - liquid)
Latin name
Mus musculus,Oryctolagus cuniculus
Tested applications:
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Rabbit (Oryctolagus cuniculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
About
Rabbits are used for polyclonal antibody production by MBS Monoclonals. Rabbit antibodies are very stable and can be stored for several days at room temperature. MBS Monoclonals adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Specificity and cross-reactivity
MHC CLASS II DQ Mouse anti Rabbit MHC class II, clone 2C4 recognises the class II RLA-DQ molecule. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rabbits, this complex is referred to as the rabbit leukocyte antigen (RLA) region. There are 3 major MHC class II proteins encoded by the RLA which are RLA P, RLA DQ and RLA DR. Mouse anti Rabbit MHC class II recognises the RLA DQ molecule, expressed by antigen presenting cells, B cells and monocytes. This antibody is reported to inhibit the mixed lymphocyte reaction by 80%. Immunoprecipitation studies yield three bands of molecular weight 28, 31 and 35 kD.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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