MOUSE Anti-PIG SLA CLASS I Antibody

431 EUR

100ug

GEN224433

N/A

N/A

N/A

N/A

IgG1

JM1E3

anticorps

Antibodies

Monoclonal

SLA CLASS I

SLA CLASS I

Mus musculus

Mouse (Mus musculus)

Mnoclonal antibodies

IgG concentration 1.0 mg/ml

Purified (Purified IgG - liquid)

Flow Cytometry (FACS), Immunoprecipitation (IP)

Pigs and the smaller guinea pigs are frequent used as models for humans.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Pig; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

SLA CLASS I The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. Clone JM1E3 recognises a monomorphic epitope expressed by porcine MHC class I molecules (SLA - 1). SLA - 1 is expressed by all nucleated porcine cells, but not on erythrocytes. This antibody has also been shown to cross-react with human MHC Class I, including HLA-E. This antibody is reported to block the interaction of MHC Class I antigens with inhibitory NK cell receptors._x000D__x000D_Removal of sodium azide is recommended prior to use in functional assays -; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.