MOUSE Anti-HUMAN SULFATASE 2 (C-TERMINAL) Antibody

271 EUR

0.025 miligrams

GEN224444

2B4

N/A

IgG1

anticorps

Antibodies

Monoclonal

SULFATASE 2

Mus musculus

Mouse (Mus musculus)

Mnoclonal antibodies

IgG concentration 1.0mg/ml

Purified (Purified IgG - liquid)

Immunohistology - Paraffin (IHC), ELISA (EIA), Western Blot (WB)

Sulf2; Sulf2; MSulf-2; AU020235; mKIAA1247; 2010004N24Rik; mSulf-2

Sulf2; Sulf2; MSulf-2; AU020235; mKIAA1247; 2010004N24Rik; mSulf-2

Sulf2; Sulf2; MSulf-2; AU020235; mKIAA1247; 2010004N24Rik; mSulf-2

extracellular sulfatase Sulf-2 isoform 1; Extracellular sulfatase Sulf-2; extracellular sulfatase Sulf-2; sulfatase 2; N/A

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

SULFATASE 2 This item recognises an epitope within the C-terminal (CT) subunit of Sulfatase 2 (Sulf-2). Sulf-2 is a novel extracellular heparan sulfate 6-O-endosulfatase, which selectively removes the critical sulfate group from the polysaccharide side chain of heparan sulfate proteoglycans (HSPGs), major components of the extracellular matrix, involved in cell differentiation, proliferation and migration. Sulf-2 acts as a modulator of several signalling proteins including Wnt proteins, bone morphogenetic proteins (BMPs) and fibroblast growth factors (FGFs), and is a direct transcriptional target of p53. Studies have linked Sulf-2 with several cancers, including breast, hepatocellular, and pancreatic cancer, and recently with non-small-cell lung carcinomas (NSCLCs) Mature human Sulf-2 is a heterodimer consisting of a 50kDa C-terminal subunit, essential for both glucosamine 6-O-sulfate-endosulfatase and arylsulfatase activity, and a 75kDa N-terminal subunit which contains the catalytic centre. Clone 2B4 specifically recognises Sulfatase 2, showing no cross-reactivity with Sulfatase 1 in either human or mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.