MOUSE Anti-PIG CD117 Antibody

431 EUR

100ug

GEN224470

N/A

N/A

IgG1

CD117

CD117

2B8/BM

anticorps

Monoclonal

Antibodies

Mus musculus

KIT; KIT; MGF; SCFR

Mouse (Mus musculus)

Mnoclonal antibodies

IgG concentration 1.0mg/ml

Purified (Purified IgG - liquid)

Pigs and the smaller guinea pigs are frequent used as models for humans.

Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistology - Frozen (IHC)

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Pig; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

mast/stem cell growth factor receptor Kit; Mast/stem cell growth factor receptor Kit; mast/stem cell growth factor receptor Kit; SCFR; c-kit; proto-oncogene c-Kit; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; N/A; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

CD117 Clone 2B8/BM is specific for porcine CD117, also known as c-kit, a 155kDa type I transmembrane protein with protein tyrosine kinase activity, which plays an important role in early haematopoiesis. Haematopoietic stem cells (HSC) of bone marrow have multilineage differentiation potential and an extensive capacity for self-renewal. The majority of adult bone marrow haematopoietic progenitor cells are CD117+ and have been used successfully in xenograft transplantation models for long term survival of grafts, without symptoms of graft-versus-host disease (GVHD). Clone 2B8/BM recognises CD117 on a small subset of porcine bone marrow progenitor cells and therefore provides an alternative tool from the previously used c-kit ligand stem cell factor, for the isolation and enrichment of porcine stem cells. Clone 2B8/BM has been shown as suitable for use on cytospins; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.