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- MOUSE Anti-HUMAN HIF2 ALPHA Antibody
Product short description
Price:
288 EUR
Size:
100ug
Catalog no.:
GEN224556
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Immunoglobulin isotype
IgG2b
French translation
anticorps
Category
Antibodies
Gene name
HIF2 ALPHA
Clonality
Monoclonal
Also known as
HIF2 ALPHA
Clone
Hif2alpha237
Latin name
Mus musculus
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Concentration
IgG concentration 1.0mg/ml
Form/Appearance
Purified (Purified IgG - liquid)
Tested applications:
Immunohistology - Paraffin (IHC)
Other gene names
EPAS1; EPAS1; HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73; BHLHE73; HIF2A; MOP2; PASD2; EPAS-1; bHLHe73; HLF; HIF-2-alpha; HIF2-alpha
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
The MOUSE Anti- HIF2 ALPHA Antibody is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from the date of dispatch.
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Other names
endothelial PAS domain-containing protein 1; Endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1; EPAS-1; HIF2-alpha; HIF-2-alpha; HIF-1alpha-like factor; HIF-1-alpha-like factor; member of PAS protein 2; PAS domain-containing protein 2; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; basic-helix-loop-helix-PAS protein MOP2; class E basic helix-loop-helix protein 73; endothelial PAS domain protein 1; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73; bHLHe73; HIF-1-alpha-like factor; HLF; Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha; Member of PAS protein 2; PAS domain-containing protein 2
Specificity and cross-reactivity
HIF2 ALPHA This item specifically recognizes human HIF2 alpha (HIF2A), otherwise known as EPAS-1 (endothelial PAS domain-containing protein 1), a nuclear transcription factor, selectively expressed by endothelial cells, which acts as an inducer of oxygen-regulated genes, during oxygen depravation (hypoxia). _x000D_HIF2A is involved in the regulation of vascular endothelial growth factor (VEGF) expression, and is implicated in vasculogenesis. Mutations in HIF2A are responsible for the autosomal dominant disorder erythrocytosis familial type 4 (ECYT4), characterized by elevated haemoglobin concentration, increased serum red blood cell mass, and haematocrit.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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