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- Mouse Monoclonal [clone OX-24] (IgG1) to Human CFH / Complement Factor H Antibody
Product short description
Price:
597 EUR
Size:
50ug
Catalog no.:
GEN245417
Product detailed description
Gene name
CFH
Gene name synonims
N/A
Immunoglobulin isotype
IgG1
Clone
OX-24
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Purification method
Protein G Purified
Form/Appearance
0.09% sodium azide.
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Also known as
CFH / Complement Factor H
Concentration
1 miligram per 1 mililiter
Other gene names
CFH; CFH; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; HF; HF1; HF2
Tested applications:
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
For long term storage, keep the antibody at -20 degrees Celsius. Short term storage of the antibody can be done at +4 degrees Celsius. Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Other names
complement factor H isoform a; Complement factor H; complement factor H; beta-1H; factor H-like 1; beta-1-H-globulin; H factor 1 (complement); H factor 2 (complement); adrenomedullin binding protein; complement factor H, isoform b; age-related maculopathy susceptibility 1; complement factor H; H factor 1
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Specificity and cross-reactivity
Recognizes the human serum complement protein factor H (155kD), binding to a different epitope from MRC OX23. The Recognizes a 43-49kD truncated form of factor H present at low level (1-5 ug/ml) in plasma and urine. In an immunoprecipitation system. Recognizes factor H in other primates, but not in cow, sheep, pig, chicken or rabbit sera. This antibody inhibits the binding of factor H to surface bound C3b, Recognizes Factor H in Western blotting procedures.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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