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- MBS Monoclonals
- Mouse Monoclonal [clone 2-22] (IgG1) to Human CASP9 / Caspase 9 Antibody
Product short description
Price:
597 EUR
Size:
50ug
Catalog no.:
GEN245551
Product detailed description
Gene name synonims
N/A
Immunoglobulin isotype
IgG1
Gene name
CASP9
Clone
42057
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Also known as
CASP9 / Caspase 9
Purification method
Protein G Purified
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Concentration
1 miligram per 1 mililiter
Form/Appearance
PBS, 0.01 mM PMSF, 50% glycerol
Tested applications:
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)
Other gene names
CASP9; CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; MCH6; CASP-9; APAF-3; ICE-LAP6
Species reactivity
Human (Homo sapiens), Monkey; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Gene
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Other names
caspase-9 isoform alpha; Caspase-9; caspase-9; apoptotic protease MCH-6; ICE-like apoptotic protease 6; apoptotic protease activating factor 3; protein phosphatase 1, regulatory subunit 56; caspase 9, apoptosis-related cysteine peptidase; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
Detects an ~46-50 kD protein, corresponding to the apparent molecular mass of the caspase-9 on SDS-PAGE immunoblots, in samples from human and monkey origins. This antibody recognizes the pro-caspase-9 human recombinant protein as well as pro-caspase -9 from human and monkey cell lysates.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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