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- Mouse Monoclonal [clone 10-1-62] (IgG) to Human CASP7 / Caspase 7 Antibody
Product short description
Price:
597 EUR
Size:
50ug
Catalog no.:
GEN245844
Product detailed description
Additional isotype
IgG
Gene name synonims
N/A
Immunoglobulin isotype
IgG
Concentration
N/A
Gene name
CASP7
Clone
22920
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Also known as
CASP7 / Caspase 7
Purification method
Protein G Purified
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Tested applications:
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Form/Appearance
PBS (10 mM sodium phosphate, pH 7.2, 50 mM sodium chloride, 0.1 mM PMSF)
Other gene names
CASP7; CASP7; MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; MCH3; CASP-7; ICE-LAP3
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Species reactivity
Hamster, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
caspase-7 isoform alpha; Caspase-7; caspase-7; apoptotic protease MCH-3; ICE-like apoptotic protease 3; caspase 7, apoptosis-related cysteine protease; caspase 7, apoptosis-related cysteine peptidase; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3
Storage and shipping
Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
Detects an ~37 kD protein, corresponding to the apparent molecular mass of the caspase-7 on SDS-PAGE immunoblots, in samples from human, mouse, rat, monkey and hamster origins. This antibody recognizes recombinant caspase-7 as well as full length pro-caspase-7 and processed enzyme from apoptotic Jurkat cell lysates.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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