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- Mouse Monoclonal [clone MEM-04] (IgG1) to Human ICAM3 / CD50 Antibody
Product short description
Price:
597 EUR
Size:
50ug
Catalog no.:
GEN245932
Product detailed description
Gene name synonims
CD50
Immunoglobulin isotype
IgG1
Gene name
ICAM3
Clone
MEM-04
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Also known as
ICAM3 / CD50
Latin name
Mus musculus
Purification method
Protein A Purified
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Concentration
1 miligram per 1 mililiter
Other gene names
ICAM3; ICAM3; CD50; CDW50; ICAM-R; ICAM-3
Tested applications:
Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS), Functional Assay
Form/Appearance
Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 mm filter sterilized.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
Other names
intercellular adhesion molecule 3; Intercellular adhesion molecule 3; intercellular adhesion molecule 3; ICAM-3; intercellular adhesion molecule-3; intercellular adhesion molecule 3; CDw50; ICAM-R; CD_antigen: CD50
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
Reacts with CD50 (ICAM-3), a 120-130 kD type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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