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- Mouse Monoclonal [clone LN-3] (IgG2b) to Human HLA-DR Antibody
Product short description
Price:
597 EUR
Size:
0.25 ml
Catalog no.:
GEN246031
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Concentration
N/A
Clone
LN-3
Immunoglobulin isotype
IgG2b
Gene name
HLA-DR
Also known as
HLA-DR
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Latin name
Mus musculus
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Tested applications:
Immunohistochemistry (IHC - Paraffin)
Other gene names
HLA-DQB1; N/A; IDDM1; CELIAC1; HLA-DQB; N/A
Form/Appearance
Serum-free culture supernatant, with 0.7% BSA and 0.1% Sodium azide.
Storage and shipping
Store antibody at the antibodys should be kept in the range of 1-7 degrees Celsius.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Other names
HLA-DR, partial; HLA-DR; HLA class II histocompatibility antigen, DQ beta 1 chain; MHC DQ beta; MHC class2 antigen; lymphocyte antigen; MHC class II antigen DQB1; MHC class II DQ beta chain; MHC class II antigen HLA-DQ-beta-1; MHC class II HLA-DQ beta glycoprotein; major histocompatibility complex, class II, DQ beta 1; HLA-DR
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
Reacts with human leukocyte antigen-DR (HLA-DR). The mAb has lymph node germinal center and mantle zone B cell reactivity. It reacts with interdigitating histiocytes in T cell zones and with sinus histiocytes and endothelial cells. It has also tumor specificity and reactivity with normal non-lymphoid tissue.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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