Mouse Monoclonal [clone 056B-214.2.4.2] (IgG1) to Human Complement C6 Antibody

597 EUR

50ug

GEN246692

C6

N/A

IgG1

anticorps

Antibodies

Monoclonal

Mus musculus

Complement C6

056B-214.2.4.2

C6; C6; N/A; N/A

Protein A Purified

Mouse (Mus musculus)

Mnoclonal antibodies

1 miligram per 1 mililiter

Borate buffered saline, 0.09% sodium azide. Sourced in Ascites.

Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS), ELISA (EIA)

complement component C6; Complement component C6; complement component C6; complement component 6; N/A

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Keep the antibody refrigerated at +4 degrees Celsius for short periods of time. For longer periods of time, freeze the antibody and keep it at -20 degrees Celsius. Cycles of freeze/thaw may reduce the activity. Store the antibodies in an undiluted form.

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.