Mouse Monoclonal [clone X75 (3C8/4)] (IgG1) to Human MUC16 / CA125 Antibody

597 EUR

100ug

GEN249130

IgG1

MUC16

CA125

anticorps

Antibodies

Monoclonal

X75 (3C8/4)

Mus musculus

MUC16 / CA125

Mouse (Mus musculus)

Mnoclonal antibodies

1 miligram per 1 mililiter

Ion exchange Chromatography

N/A; MUC16; N/A; CA125; MUC-16; CA-125

Tris buffered saline, 0.09% sodium azide.

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

mucin-16; Mucin-16; N/A; N/A; Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

For long term storage, keep the antibody at -20 degrees Celsius. Short term storage of the antibody can be done at +4 degrees Celsius. Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity.

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Specific for Mucin 16, also known as Ovarian Cancer Antigen CA-125. Recognizes epitope specificity group B (ISOBM classification) similar to M-11. Mucin 16 is a serum marker, overexpressed in epithelial ovarian cancer cells and is routinely used for patient monitoring. CA-125 was originally identified by Bast et al. using a monoclonal antibody developed against the ovarian cancer cell line OVCA433; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.