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- Nephrin, phosphorylated (Tyr1176/Tyr1193) (NPHN, CNF, Nephrosis 1 Congenital Finnish Type, NPHS1, Renal Glomerulus-specific Cell Adhesion Receptor) Antibody
Product short description
Price:
603 EUR
Size:
100ul
Catalog no.:
GEN632703
Product detailed description
Immunoglobulin isotype
IgG
Concentration
N/A
Tissue
cell
Clone
9H482
Also known as
Nephrin
French translation
anticorps
Disease
congenital
Category
Antibodies
Clonality
Monoclonal
Purification method
Supernatant
Tested applications:
Western Blot (WB)
Source organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Host organism
Rabbit (Oryctolagus cuniculus)
Other gene names
NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN
Gene name synonims
NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN
Gene name
NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN
Form/Appearance
Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Other names
nephrin; Nephrin; nephrin; renal glomerulus-specific cell adhesion receptor; nephrosis 1, congenital, Finnish type (nephrin); Renal glomerulus-specific cell adhesion receptor
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivity
Recognizes Nephrin at ~180/135kD phosphorylated on tyrosines 1176 and 1193. Does not recognize non-phosphorylated Nephrin. Species Crossreactivity: Human.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Nephrin, phosphorylated (Tyr1176/Tyr1193) (NPHN, CNF, Nephrosis 1 Congenital Finnish NPHS1, Renal Glomerulus-specific Adhesion Receptor) Antibody.For cells, cell lines and tissues in culture till half confluency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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