Product short description
Price:
735 EUR
Size:
200ug
Catalog no.:
GEN311781
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Immunoglobulin isotype
IgG1
Clone
SZ.22
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Other names
CD41 antigen; N/A
Subcategory
Mnoclonal antibodies
Also known as
CD41, Platelet gpIIb IIIa
Purification method
Protein A chromatography.
Tested applications:
Flow Cytometry, Western Blot
Concentration
0.2mg/ml (prior to lyophilization)
Form/Appearance
Purified, Lyophilized Reconstitute with 1ml distilled water.
Host organism
Mouse (Mus musculus). Hybridization of X63-Ag14 myeloma cells with spleen cells from BALB/c mice. Source: Ascites
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage of the reconstituted form for up to 1 month at 2 to 8 degree C.
Specificity and cross-reactivity
CD41, Platelet gpIIb IIIa The molecular weight of the recognized antigen is 135kDa. CD41 is the integrin alpha IIb chain, also called gpIIb, which is non-covalently associated with the integrin beta 3 chain, also called gpIIIa (CD61), forming the gpIIbIIIa complex. Reacts with the alpha chain of gpIIb independently of the presence of gpIIIa. It reacts specifically with normal platelets and megakaryocytes but studeis have shown that it does not react with Glanzamann's thrombasthenic platelets which lack the membrane glycoprotein gpIIbIIIa. Does not inhibit the platelet aggregation and secretion induced by collagen, arachidonic acid and thrombin. Does not inhibit the fibrinogen binding to human platelets induced by ADP, arachidonic acid and PAF.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.