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- MBS Monoclonals
- MAb to EGFR activated pTyr1173 Antibody
Product short description
Price:
989 EUR
Size:
100ug
Catalog no.:
GEN312927
Product detailed description
Clone
9H2
Immunoglobulin isotype
IgG1
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Concentration
500ug/1000ul
Form/Appearance
Biotin, Liquid
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus) Source: Cell culture
Other gene names
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
Gene name synonims
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
Gene name
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
Purification method
Thiophilic adsorption and size exclusion chromatography
Tested applications:
ELISA, Immunocytochemistry, Immunohistochemistry(f, p), IP, Western Blot
Also known as
Epidermal Growth Factor Receptor (EGFR), phospho-Tyr 1173 & Positive Control
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Aliquot and store at -80 degree C. Thawed aliquots may be stored at the antibodys should be kept in the range of 1-7 degrees Celsius. for up to 3 months.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
epidermal growth factor receptor; Epidermal growth factor receptor; epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Specificity and cross-reactivity
Epidermal Growth Factor Receptor (EGFR), phospho-Tyr 1173 & Positive Control Binding of EGF to the extracellular domain of the EGF-receptor results in receptor dimerization and tophosphorylation on tyrosine residues, Y1173 being the major autophosphorylation site. Clone 9H2 specifically interacts with the 1170 - NAEpYLRV motif corresponding to the major autophosphorylation site of human EGFR. The antibody does not interact with the non-phosphorylated EGFR nor with unrelated Tyrosine-phosphorylated proteins. This phosphorylation site-specific monoclonal antibody allows the detection and quantification of activated EGFR in crude cell extracts in Immunoblot, ELISA and Biosensor assay formats without the use of P32. Reacts with Human, mouse, and dog.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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