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- MBS Monoclonals
- NFkB, p65, phosphorylated (Ser536) (NF Kappa B, NF-kB, Nuclear Factor kappa B) Antibody
Product short description
Price:
603 EUR
Size:
100ul
Catalog no.:
GEN633051
Product detailed description
Immunoglobulin isotype
IgG
Concentration
N/A
Clone
4i11
French translation
anticorps
Also known as
NFkB, p65
Category
Antibodies
Clonality
Monoclonal
Purification method
Supernatant
Source organism
Human (Homo sapiens)
Subcategory
Mnoclonal antibodies
Host organism
Rabbit (Oryctolagus cuniculus)
Other gene names
NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
Gene name synonims
NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
Gene name
NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
Tested applications:
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Form/Appearance
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, 50% glycerol.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Hamster, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Porcine, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Detects NF-kB p65 only when phosphorylated at serine 536. Does not crossreact with the p50 subunit or other related proteins. Species Crossreactivity; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c; NF-kappa-B inhibitor-interacting Ras-like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; I-kappa-B-interacting Ras-like protein 2
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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