Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438125
Product detailed description
Gene name
TG
Gene name synonims
N/A
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Clone
2H11+6E1
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Also known as
Thyroglobulin
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Other gene names
TG; TG; TGN; AITD3; Tg
Immunoglobulin isotype
IgG1, kappa + IgG1, kappa
Other names
thyroglobulin; Thyroglobulin; thyroglobulin; thyroglobulin; N/A
Tested applications:
Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistology (IH)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.