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- MBS Monoclonals
- TAG-72 Antibody
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438364
Product detailed description
Purification method
N/A
Form/Appearance
N/A
Concentration
N/A
Also known as
TAG-72
Clone
SPM536
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG1, kappa
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Other gene names
tag-72; tag-72; N/A; N/A
Gene name synonims
tag-72; tag-72; N/A; N/A
Gene name
tag-72; tag-72; N/A; N/A
Other names
Protein TAG-72; mRNA cap guanine-N7 methyltransferase; Protein TAG-72; N/A; mRNA (guanine-N(7)-)-methyltransferase
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens), Cow, Dog, Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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