Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438396
Product detailed description
Gene name synonims
N/A
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name
MCAM
Clone
OJ79c
Also known as
MUC18
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG1, kappa
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Other gene names
MCAM; MCAM; CD146; MUC18; MUC18
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Tested applications:
ELISA (For coating, order antibody without BSA), Flow Cytometry (0.5-1ug/million cells), Immunofluorescence (0.5-1.0ug/ml), Immunoprecipitation (1-2ug/500ug protein), Western Blot (0.5-1.0ug/ml), Immunohistology (Frozen) (0.5-1.0ug/ml for 30 min at RT Opt
Other names
N/A; Cell surface glycoprotein MUC18; cell surface glycoprotein MUC18; Gicerin; melanoma adhesion molecule; cell surface glycoprotein P1H12; melanoma-associated antigen A32; melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; melanoma cell adhesion molecule; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD_antigen: CD146
Specificity and cross-reactivity
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.