Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438419
Product detailed description
Gene name synonims
N/A
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Also known as
NKX2.2
Gene name
NKX2-2
Clone
NX2/294
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG2b, kappa
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Other gene names
NKX2-2; NKX2-2; NKX2B; NKX2.2; NKX2.2; NKX2B
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
homeobox protein Nkx-2.2; Homeobox protein Nkx-2.2; homeobox protein Nkx-2.2; NK-2 homolog B; homeobox protein NK-2 homolog B; NK2 transcription factor-like protein B; NK2 transcription factor related, locus 2; NK2 homeobox 2; Homeobox protein NK-2 homolog B
Specificity and cross-reactivity
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.