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- MBS Monoclonals
- CD1a Antibody
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438502
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Concentration
N/A
Form/Appearance
N/A
Also known as
CD1a
Gene name
CD1A
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Clone
O10+C1A/711
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Immunoglobulin isotype
IgG1, kappa + IgG1, kappa
Other gene names
CD1A; CD1A; R4; T6; CD1; FCB6; HTA1; hTa1 thymocyte antigen
Tested applications:
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
T-cell surface glycoprotein CD1a; T-cell surface glycoprotein CD1a; T-cell surface glycoprotein CD1a; hTa1 thymocyte antigen; CD1A antigen, a polypeptide; cluster of differentiation 1 A; T-cell surface antigen T6/Leu-6; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; CD1a molecule; T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; CD_antigen: CD1a
Specificity and cross-reactivity
At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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