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- MBS Monoclonals
- Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cell Specific Transcription Factor 1 alpha, TCF1 alpha) Antibody
Product short description
Price:
                                                                                    768 EUR
                                                                            
                                Size:
                                        100ug
                                    
                                Catalog no.:
                                        GEN600490
                                    
                                Product detailed description
Concentration
                                        N/A
                                    
                                Tissue
                                        cell
                                    
                                Immunoglobulin isotype
                                        IgG1
                                    
                                Clone
                                        6D538
                                    
                                French translation
                                        anticorps
                                    
                                Category
                                        Antibodies
                                    
                                Clonality
                                        Monoclonal
                                    
                                Host organism
                                        Mouse (Mus musculus)
                                    
                                Subcategory
                                        Mnoclonal antibodies
                                    
                                Also known as
                                        Lymphoid Enhancer Factor 1
                                    
                                Tested applications:
                                        Western Blot (WB), Immunocytochemistry (ICC)
                                    
                                Purification method
                                        Highly Purified by size exclusion chromatography.
                                    
                                Other gene names
                                        LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha
                                    
                                Gene name synonims
                                        LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha
                                    
                                Gene name
                                        LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha
                                    
                                Form/Appearance
                                        Supplied as a liquid in PBS, 0.1% sodium azide, PEG and sucrose, before the addiition of glycerol to 40%.
                                    
                                Properties
                                        If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
                                    
                                Species reactivity
                                        Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
                                    
                                Other names
                                        lymphoid enhancer-binding factor 1 isoform 1; Lymphoid enhancer-binding factor 1; lymphoid enhancer-binding factor 1; TCF1-alpha; T cell-specific transcription factor 1-alpha; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha
                                    
                                Specificity and cross-reactivity
                                        Recognizes human and mouse LEF. Does not cross-react with T cell factor 3 (TCF3) or T cell factor 4 (TCF4). Detects a band of ~68kDa by Western blot.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
                                    
                                Storage and shipping
                                        Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
                                    
                                Description
                                        The Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T Specific Transcription Factor 1 alpha, TCF1 alpha) Antibody is a α- or alpha protein sometimes glycoprotein present in blood.For cells, cell lines and tissues in culture till half confluency.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
                                    
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