Nuclear Receptor LXR alpha, Ligand Binding Domain (NR1H3, RLD-1) Antibody

812 EUR

100ug

GEN602384

N/A

5L2

IgG2a

anticorps

Antibodies

Monoclonal

Mnoclonal antibodies

Mouse (Mus musculus)

Human (Homo sapiens)

LOC100352900; N/A; NR1H3; LXR-alpha; N/A

LOC100352900; N/A; NR1H3; LXR-alpha; N/A

LOC100352900; N/A; NR1H3; LXR-alpha; N/A

Purified by ammonium sulfate precipitation.

Nuclear Receptor LXR alpha, Ligand Binding Domain

Supplied as a liquid in physiologic saline, 0.1% sodium azide.

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

nuclear receptor subfamily 1, group H, member 3; N/A; nuclear receptor subfamily 1, group H, member 3; liver X receptor alpha; N/A; N/A

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Human (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes human LXR alpha at ~50kD. Does not crossreact with human LXR beta. Species Crossreactivity: rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

The Receptor LXR alpha, Ligand Binding Domain (NR1H3, RLD-1) Antibody is a α- or alpha protein sometimes glycoprotein present in blood.FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.