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- MBS Monoclonals
- Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1) Antibody
Product short description
Price:
1475 EUR
Size:
0.25 miligrams
Catalog no.:
GEN604030
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Concentration
N/A
Other gene names
N/A
Immunoglobulin isotype
IgM
Other names
N/A
Clone
8J189
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Source organism
Mouse (Mus musculus)
Host organism
Rat (Rattus norvegicus)
Purification method
Purified by ammonium sulfate precipitation.
Tested applications:
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Form/Appearance
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
Also known as
Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1) Antibody.Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Specificity and cross-reactivity
Recognizes mouse SIGN-R1, a C-type lectin that has been identified as a murine homolog of the human CD-SIGN related molecule, L-SIGN. Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, medullary and subcapsular sinus macrophages in the lymph nodes, and at lower levels on liver sinusoidal endothelial cells. SIGN-R1 has not been detected on murine dendritic cell populations. Blocks the uptake of neutral polysaccharides by macrophages.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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