STAT 5a,b, phosphorylated (Tyr694/Tyr699) (Signal Transducer and Activator of Transcription 5a,b) Antibody

625 EUR

100ug

GEN605235

IgG

N/A

0.T.141

anticorps

STAT 5a,b

Antibodies

Monoclonal

Western Blot (WB)

Mnoclonal antibodies

Mouse (Mus musculus)

Human (Homo sapiens)

STAT5A; STAT5A; MGF; STAT5; STAT5

STAT5A; STAT5A; MGF; STAT5; STAT5

STAT5A; STAT5A; MGF; STAT5; STAT5

Affinity Purified by Protein G affinity chromatography.

Supplied as a liquid in 0.1M Tris-glycine, 0.15M sodium chloride, 0.05% sodium azide.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

signal transducer and activator of transcription 5A; Signal transducer and activator of transcription 5A; signal transducer and activator of transcription 5A; OTTHUMP00000198376; signal transducer and activator of transcription 5A; N/A

Bovine, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes the phosphorylated tyrosine residues 694 of human STAT5A, 94kD and 699 of STAT5B, 92kD.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.