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- MBS Monoclonals
- Leptin Receptor (OBR, LEPR, B219, Obese Receptor) Antibody
Product short description
Price:
603 EUR
Size:
100ug
Catalog no.:
GEN606437
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
5i316
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Also known as
Leptin Receptor
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Purification method
Affinity Purified by Protein G affinity chromatography.
Other gene names
LEPR; LEPR; OBR; OB-R; CD295; LEP-R; DKFZp686B1731; DB; OBR
Gene name synonims
LEPR; LEPR; OBR; OB-R; CD295; LEP-R; DKFZp686B1731; DB; OBR
Gene name
LEPR; LEPR; OBR; OB-R; CD295; LEP-R; DKFZp686B1731; DB; OBR
Tested applications:
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Form/Appearance
Supplied as a lyophillized powder from 0.05M PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
leptin receptor; Leptin receptor; leptin receptor; huB219; OB receptor; OTTHUMP00000010692; OTTHUMP00000010693; OTTHUMP00000010694; OTTHUMP00000010695; leptin receptor; HuB219; OB receptor
Specificity and cross-reactivity
Recognizes human Leptin Receptor. Does not react with mouse. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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