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- MBS Monoclonals
- TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA) (Biotin) Antibody
Product short description
Price:
509 EUR
Size:
100ug
Catalog no.:
GEN632305
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Concentration
N/A
Clone
R73
Immunoglobulin isotype
IgG1
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Conjugation
Biotinylated
Tissue
cell, region
Also known as
TCR, alpha, beta
Other names
TCR, partial; N/A
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Source organism
Rat (Rattus norvegicus)
Tested applications:
Flow Cytometry (FC/FACS)
Storage and shipping
Store the antibody at -20 degrees Celsius.
Purification method
Highly Purified by Ion Exchange chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Species reactivity
Monkey, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Specificity and cross-reactivity
Detects a T cell specific molecule consisting of two disulphide-linked subunits of 40 and 46kD molecular weight, respectively, on 97% of peripheral rat T cells as defined by the OX-52 marker. 3H2910 is mitogenic for unseparated spleen cells and for purified T cells. In the rat thymus, mature medullary cells express the 3H2910 determinant at the same level as peripheral T cells, whereas 94% of CD4- CD8- thymocytes are 3H2910 negative. It is most likely directed at a constant determinant of the rat alpha/beta heterodimeric T cell antigen receptor. Species Crossreactivity: Clone is reported to crossreact with Cynomolgus monkey (4).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
The TCR, alpha, beta (T Receptor, T- Receptor beta-1 Chain C Region, TRBC1, T- Receptor alpha Chain C Region, TRAC, TCRA) ( ) Antibody is a α- or alpha protein sometimes glycoprotein present in blood.For cells, cell lines and tissues in culture till half confluency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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