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- MBS Monoclonals
- Progesterone Receptor, pHOSPHORYLATED (Ser190) Antibody
Product short description
Price:
835 EUR
Size:
100ul
Catalog no.:
GEN633345
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
6A455
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Other gene names
PGR; PGR; PR; NR3C3; NR3C3
Gene name synonims
PGR; PGR; PR; NR3C3; NR3C3
Gene name
PGR; PGR; PR; NR3C3; NR3C3
Also known as
Progesterone Receptor, pHOSPHORYLATED
Tested applications:
Western Blot (WB), Immunohistochemistry (IHC)
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a liquid in 10mM HEPES, pH 7.5, 0.1% BSA, 0.09% BSA and 50% glycerol.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
progesterone receptor; Progesterone receptor; progesterone receptor; OTTHUMP00000236114; OTTHUMP00000236115; OTTHUMP00000236117; OTTHUMP00000236119; nuclear receptor subfamily 3 group C member 3; progesterone receptor; Nuclear receptor subfamily 3 group C member 3
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
Specificity and cross-reactivity
Specific for human progesterone receptor, when phosphorylated at serine 190. Recognizes both PR-A and PR-B, when phosphorylated at serine 190. The specificity of this antibody has been shown by blocking studies in Western blotting, whereby staining was blocked by the phosphopeptide. No blocking was seen by the corresponding non-phosphopeptide.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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