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- MBS Monoclonals
- LSD1 antibody
Product short description
Price:
459 EUR
Size:
100ul
Catalog no.:
GEN533091
Product detailed description
Gene name synonims
N/A
Other gene names
N/A
Purification method
N/A
Also known as
LSD1
Gene name
LSD1
Immunoglobulin isotype
IgG1
Clone
1B2E5
Other names
LSD1; N/A
French translation
anticorps
Concentration
1.0 mg/ml
Clonality
Monoclonal
Category
Antibodies
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Tested applications:
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Form/Appearance
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Specificity and cross-reactivity
N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Monkey; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
For optimal storage conditions, keep the antibody at +4°C. Temperature variations in the range 1°C to 9°C are tolerable. for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene
Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
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