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- Monoclonal mouse anti-human interleukin-1, beta (IL-1, beta)
Product short description
Price:
564 EUR
Size:
1000ug
Catalog no.:
GEN660044
Product detailed description
Gene name synonims
N/A
Host organism
N/A
Concentration
N/A
Gene name
IL-1
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Also known as
Interleukin-1
Clone
6E10, 11E5, 5C10
Subcategory
Mnoclonal antibodies
Tested applications:
Immunohistdegree Chemistry (IHC)
Purification method
Chromatography on protein A Sepharose
Form/Appearance
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage and shipping
Store the antibody at +4 degrees Celsius.
Other gene names
IL1B; IL1B; IL-1; IL1F2; IL1-BETA; IL1F2; IL-1 beta
Immunoglobulin isotype
IgG2a for MAb 6E10 IgG2b for MAb 11E5 IgM for MAb 5C10
Other names
interleukin 1, beta; Interleukin-1 beta; interleukin-1 beta; IL-1 beta; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta; interleukin 1, beta; Catabolin
Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Specificity and cross-reactivity
MAbs react with three different determinants on IL-1, beta molecule. MAbs do not inhibit the biological activity of IL-1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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