Monoclonal mouse anti-human IgE

459 EUR

1000ug

GEN660045

IgE

IgE

IgE

N/A

N/A

N/A

N/A

N/A

Monoclonal

Antibodies

Mus musculus

Mnoclonal antibodies

ELISA (EIA), Western Blot (WB)

5D4, E411, XTE4, BE5, 4G7, 4H10, IEF6

Store the antibody at +4 degrees Celsius.

IgG for MAbs BE5, 4G7 and 4H10 IgG1 for MAbs XTE4 and IEF6 IgG2a for MAbs 5D4 and E411

MAbs 5D4, E411, BE5, 4G7, 4H10 and IEF6 in PBS, pH 7.4, 0.1 % sodium azide (NaN‚ƒ) XTE4 in 0.15 M NaCl, 10 mM Tris, pH 7.5, 0.05 % sodium azide (NaN‚ƒ).

MAbs 5D4, E411, BE5, 4G7 and 4H10 by chromatography on protein A Sepharose MAb IEF6 by chromatography on protein G Sepharose MAb XTE4 by ion exchange chromatography

N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

MAb E411 class specific for human IgE, Fc-region specific MAb 5D4 - IgE Cɛ2-domain specific MAb XTE4 - epsilon chain specific; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.