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- Monoclonal mouse anti-human leptin
Product short description
Price:
796 EUR
Size:
1000ug
Catalog no.:
GEN660070
Product detailed description
Host organism
N/A
Concentration
N/A
Tested applications:
N/A
Also known as
Leptin
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Immunoglobulin isotype
IgG1 for all MAbs
Subcategory
Mnoclonal antibodies
Gene name
lep; N/A; ob; xlep; N/A
Gene name synonims
lep; N/A; ob; xlep; N/A
Other gene names
lep; N/A; ob; xlep; N/A
Clone
3G7, 4F8, 4F12, 5F10, 9C10, 10H1
Form/Appearance
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage and shipping
Store the antibody at +4 degrees Celsius.
Other names
leptin; N/A; leptin; obesity homolog; leptin
Purification method
MAb 4F12: Chromatography on protein A Sepharose and gel filtration, other MAbs: Chromatography on protein A Sepharose
Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Specificity and cross-reactivity
MAbs recognize recombinant human leptin and leptin circulating in human blood.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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