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- Monoclonal mouse anti-T-cell receptor (TCR)
Product short description
Price:
829 EUR
Size:
1000ug
Catalog no.:
GEN660321
Product detailed description
Gene name
TCR
Gene name synonims
N/A
Other gene names
N/A
Concentration
N/A
Host organism
N/A
Tissue
cell
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Also known as
T-cell receptor
Tested applications:
Peptide ELISA (EIA)
Subcategory
Mnoclonal antibodies
Other names
T cell receptor, partial; N/A
Purification method
Chromatography on protein G Sepharose
Form/Appearance
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage and shipping
Store the antibody at +4 degrees Celsius.
Clone
VB1-F10, VB2-A4, VB7-D10, VB7-B9, C5C1, C5D1, VB17-E5, VB17-F11
Immunoglobulin isotype
IgG1 for MAbs VB1-F10, VB2-A4, C5C1, C5D1, VB17-E5, VB17-F11 IgG2a for MAbs VB7-D10, VB7-B9
Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
MAb VB1-F10: TCR, variable beta-chain, family 1, peptide CTSNEGSKATYEQGV MAb VB2-A4: TCR, variable beta-chain, family 2, peptide QYYNGEERAKGNI MAbs VB7-D10, VB7-B9: TCR, variable beta-chain, family 7, Peptide KQKAKKPPEL MAbs C5C1, C5D1: TCR, variable beta-chain, family 14, peptide VEVTDKGDVPEGYK MAbs VB17-E5, VB17-F11: TCR, variable beta-chain, family 17, Peptide FQKGDIAEGY.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.For cells, cell lines and tissues in culture till half confluency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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