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- Rat Anti-Mouse TNF-a-UNLB
Product short description
Price:
348 EUR
Size:
500ug
Catalog no.:
GEN670095
Product detailed description
Concentration
N/A
Purification method
N/A
Clone
MP6-XT22
Also known as
TNF- alpha
Category
Antibodies
Clonality
Monoclonal
Immunoglobulin isotype
Rat IgG1 kappa
Subcategory
Mnoclonal antibodies
Host organism
Rat (Rattus norvegicus)
Form/Appearance
Purified (UNLB) Antibody
Latin name
Mus musculus,Rattus norvegicus
Tested applications:
ELISA; Flow Cytometry; Western Blot
Gene name
TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2
Gene name synonims
TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2
Other gene names
TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Specificity and cross-reactivity
Mouse Tumor Necrosis Factor- alpha (TNF- alpha)1-3; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
TNF-alpha; Tumor necrosis factor; tumor necrosis factor; TNF-a; cachectin; APC1 protein; OTTHUMP00000029281; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
Storage and shipping
The purified (UNLB) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The biotin (BIOT) conjugate is supplied as 0.5 mg labeled antibody in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Reagents are stable for the period shown on the label if stored as directed.
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