Mouse Anti-Human SMAC/DIABLO-UNLB

459 EUR

100ug

GEN670144

N/A

N/A

2D12

Antibodies

Monoclonal

Mouse IgG2b

SMAC/DIABLO

Mus musculus

ELISA; Western Blot

Mouse (Mus musculus)

Mnoclonal antibodies

Purified (UNLB) Antibody

DIABLO; DIABLO; SMAC; SMAC3; DIABLO-S; FLJ10537; FLJ25049; N/A

DIABLO; DIABLO; SMAC; SMAC3; DIABLO-S; FLJ10537; FLJ25049; N/A

DIABLO; DIABLO; SMAC; SMAC3; DIABLO-S; FLJ10537; FLJ25049; N/A

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. Reagents are stable for the period shown on the label if stored as directed.

Smac/DIABLO-S protein; Diablo homolog (Drosophila); diablo homolog, mitochondrial; 0610041G12Rik; OTTHUMP00000211306; OTTHUMP00000211307; OTTHUMP00000211309; OTTHUMP00000239748; OTTHUMP00000239749; mitochondrial Smac protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; diablo, IAP-binding mitochondrial protein; N/A

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Human SMAC/DIABLO SMAC/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. SMAC/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor of apoptosis protein (IAP) family, a major group of apoptosis regulators that have been shown to directly block caspase activity thereby blocking apoptosis. 1-6; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.