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- MBS Monoclonals
- Mouse Anti-Human CD34-APC
Product short description
Price:
448 EUR
Size:
100 Tests
Catalog no.:
GEN670179
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Concentration
N/A
Purification method
N/A
Other names
N/A
Immunoglobulin isotype
IgG1
Also known as
CD34C
Clonality
Monoclonal
Category
Antibodies
Latin name
Mus musculus
Clone
581 (Class III)
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Form/Appearance
Allophycocyanin (APC) Conjugate
Tested applications:
Flow Cytometry, Immunohistochemistry (Frozen sections)
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
The allophycocyanin (APC) conjugate is supplied as 100 tests in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze!
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
Stem cell or hematopoietic marker. The most used affinity clone is QBEND10. We compare the affinity to this clone.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Specificity and cross-reactivity
Human CD34 Class III epitope CD34 is a 110-120 kDa heavily O-glycosylated type I transmembrane glycoprotein. It is expressed on a small subpopulation (2-4%) of bone marrow cells including hematopoietic stem cells, small vessel endothelial cells and tumors of epithelial origin, and a subset of fibroblasts. It is believed that hematopoietc CD34 plays a role in modulating adhesion and as well as signal tranduction through its phosphorylation by activated protein kinase C. The monoclonal antibody 581 reacts to the class III CD34 epitope which is resistant to neuraminidase, chymopapain and glycoprotease.1-8; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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