Mouse Anti-Human CD51/61-UNLB

260 EUR

100ug

GEN670233

N/A

N/A

N/A

N/A

N/A

N/A

IgG1

23C6

CD51/61

Antibodies

Monoclonal

Mus musculus

Mnoclonal antibodies

Mouse (Mus musculus)

Purified (UNLB) Antibody

Flow Cytometry, Immunohistochemistry (Frozen sections), Immunoprecipitation, Blocking of adhesion

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

The purified (UNLB) antibody is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of phosphate buffered saline containing 0.1% PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius..

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Human CD51/61 CD51/61, also known as the alphaVbeta3 integrin and the vitronectin receptor, is a heterodimeric cell surface glycoprotein complex. It is expressed in high amounts on osteoclasts, endothelial cells and melanoma cells. CD51/61 is also found on activated T cells, mast cells, platelets and NK cells. Ligands for CD51/61 include vitronectin, fibronectin, laminin, thrombospondin and von Willebrand-factor. It also mediates cell to cell adhesion via its association with CD31/PECAM-1.1-9; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.