Mouse Anti-Human IL-33-UNLB

426 EUR

500ug

GEN670254

N/A

N/A

IL-33

IgG2a

ELISA

SB127j1

Monoclonal

Antibodies

Mus musculus

Mouse (Mus musculus)

Mnoclonal antibodies

Purified (UNLB) Antibody

IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV

IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV

IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

The purified (UNLB) antibody is supplied as 0.5mg purified immunoglobulin in 1.0mL of 100mM borate buffered saline, pH 8.2; Store the antibody ats should be kept in the range of 1-7 degrees Celsius..

interleukin-33 isoform 3; Interleukin-33; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules; interleukin 33; Interleukin-1 family member 11; IL-1F11; Nuclear factor from high endothelial venules

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Reacts with human IL-331 Interleukin-33 (IL-33), also known as NF-HEV, is a 30kD protein and a recently identified member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells, but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways2. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-kappaB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5 and IL-133,4. In vivo administration of this cytokine in mice resulted in eosinophilia and splenomegaly, as well as induced severe pathological changes in the lungs, gastrointestinal tract and other mucosal organs3,5,6; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.