Mouse Anti-Human CD86/B7-2-SPRD

503 EUR

100 Tests

GEN670280

N/A

N/A

N/A

N/A

N/A

N/A

IgG1

BU63

Antibodies

Monoclonal

Mus musculus

CD86/B7-2-SPRD

Mnoclonal antibodies

Mouse (Mus musculus)

Spectral Red (SPRD) Conjugate

Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen sections), Western Blot

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

The Spectral Red (SPRD) conjugate is supplied as 100 tests in 0.5 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze!

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Human CD86/B7-2 CD86, also known as B70/B7-2, is a 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily. It is expressed at high levels on resting monocytes and dendritic cells and at very low levels on resting B and T lymphocytes. Activation of B cells, T cells and monocytes leads to upregulation of CD86 expression. Like CD80, CD86 is a ligand of CD28 and CD152. The interactions of CD86 (and CD80) with CD28 provides important costimulatory signals to T cells activated via the CD3/TCR complex. CD86 is expressed earlier than CD80 and appears to dominate in the primary immune response.1-3; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.