Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438019
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name synonims
N/A
Also known as
EGFR
Gene name
EGFR
Clone
GFR450
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG2a, kappa
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Tested applications:
Immunohistology (IH)
Other gene names
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB; ERBB1; HER1
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Specificity and cross-reactivity
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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