Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438147
Product detailed description
Also known as
CD5
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name
CD5
Gene name synonims
N/A
Clonality
Monoclonal
Category
Antibodies
Clone
C5/473+CD5/54/F6
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
CD5; CD5; T1; LEU1; LEU1
Immunoglobulin isotype
IgG1, kappa + IgG1, kappa
Tested applications:
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
T-cell surface glycoprotein CD5; T-cell surface glycoprotein CD5; T-cell surface glycoprotein CD5; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1; CD5 molecule; Lymphocyte antigen T1/Leu-1; CD_antigen: CD5
Specificity and cross-reactivity
Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.