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- CD104 (Integrin Beta-4)
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438251
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name synonims
N/A
Clone
UM-A9
Gene name
ITGB4
Also known as
CD104
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG2a, kappa
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
ITGB4; ITGB4; CD104; N/A
Other names
integrin beta-4 isoform 1; Integrin beta-4; integrin beta-4; GP150; CD104 antigen; integrin beta-4 subunit; integrin, beta 4; GP150; CD_antigen: CD104
Tested applications:
Biological Blockade, ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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