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- MBS Monoclonals
- Cytokeratin, Basic (Type II or HMW)
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438272
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name
KRT1
Immunoglobulin isotype
IgG1
Clone
SPM116
Clonality
Monoclonal
Category
Antibodies
Also known as
Cytokeratin
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Gene name synonims
KRT3; KRT4; KRT5; KRT6; KRT8
Other gene names
KRT1; KRT1; K1; CK1; EHK; EHK1; EPPK; KRT1A; NEPPK; KRTA; CK-1; K1
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology (IH)
Description
Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens), Monkey, Cow, Dog, Rabbit (Oryctolagus cuniculus), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
keratin, type II cytoskeletal 1; Keratin, type II cytoskeletal 1; keratin, type II cytoskeletal 1; CK-1; cytokeratin 1; cytokeratin-1; 67 kDa cytokeratin; hair alpha protein; type-II keratin Kb1; epidermolytic hyperkeratosis 1; keratin 1; 67 kDa cytokeratin; Cytokeratin-1; CK-1; Hair alpha protein; Keratin-1; K1; Type-II keratin Kb1
Specificity and cross-reactivity
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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